| Shwartzman phenomenon [`shwȯrts·mǝn fǝ´näm·ǝ´nän] IMMUNOLOGY A type of local tissue reactivity in the skin in which a preparatory injection of the endotoxin is followed by an intravenous injection of the same or another endotoxin 24 hours later, producing immediate neutropenia and thrombopenia with the development of leukocyte- platelet thrombi with subsequent hemorrhage. |